Denne undersøgelse undersøger argininvasopressins (AVP) rolle i moderlig aggression hos diegivende rotter. Resultaterne viser, at AVP ikke påvirker antallet af angreb, men forsinker aggression og reducerer moderlig adfærd, mens en V1a-receptorantagonist øger moderlig aggression. Det tyder på, at AVP påvirker både moderlig aggression og adfærd under diegivning.
Titel på undersøgelse:
Central actions of arginine vasopressin and oxytocin.
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Hele abstrakt på originalsprog:
Maternal aggression is a robust type of aggression displayed by lactating female rats. Although arginine vasopressin (AVP) has been implicated in the control of male aggression, its involvement in maternal aggression has not been thoroughly investigated. Previous neuroanatomical studies suggest that AVP may mediate the display of aggression during lactation. In the current study, AVP and an AVP V1a receptor antagonist were centrally administered to primiparous rats on days 5 and 15 of lactation, and aggression, maternal behavior, and grooming were recorded. Although AVP did not affect the number of attacks or duration of aggression, it increased the latency to initiate aggression on day 5, in addition to decreasing maternal behavior and increasing grooming. Conversely, V1a antagonist treatment increased maternal aggression on both days of lactation, decreased maternal behavior on day 15, and decreased grooming on day 5. Thus, it appears that central AVP activity modulates maternal aggression, as well as maternal behavior and grooming behavior during lactation.