Titel på undersøgelse:

Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review.

Forfattere: Khani, P., Ansari Dezfouli, M., Nasri, F., Rahemi, M., Ahmadloo, S., Afkhami, H., Saeidi, F., Tereshchenko, S., Bigdeli, M. R., & Modarressi, M. H. | År: 23 | Kapitel:

En systematisk gennemgang af studier undersøgte, hvordan genetik og epigenetik påvirker romantiske relationer. Forskere identificerede 15 gener involveret i oxytocin-, serotonin- og dopamin-signalveje. Disse genetiske variationer påvirker parforholdets kvalitet og tilpasning. Resultaterne viser, at både arv og miljø spiller en rolle i romantiske relationer.

Hele abstrakt på originalsprog:

Couples’ relationships are shaped by a complex interplay between partners and their intrapersonal traits, with romantic relationships and love being closely tied to marital satisfaction, stability, and overall happiness and health. Personality traits, influenced by both genetic and non-genetic factors such as socioeconomic status and external appearance, significantly affect the quality of romantic relationships. To explore the role of genetics and epigenetic factors in romantic relationships, we conducted a scoping systematic review, searching PubMed, EMBASE, Web of Science, Scopus, and APA PsycInfo for relevant articles from inception to June 4, 2022. Our review identified studies examining polymorphisms in 15 genes or chromosomal regions, which we categorized into four groups: (1) oxytocin-related signaling pathway (OXTR, CD38, AVPR1A); (2) serotonin-related signaling pathway (SLC6A4, HTR1A, HTR2A); (3) dopamine and catecholamine-related signaling pathway (DRD1, DRD2, DRD4, ANKK1, COMT); and (4) other genes (HLA, GABRA2, OPRM1, Y-DNA haplogroup D-M55), subsequently extracting significant polymorphisms impacting couple adjustment and romantic relationships. Collectively, the findings indicate that genetic and epigenetic variants play a critical role in shaping marital adjustment and the dynamics of romantic relationships over time.